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Liposomal drug formulations in cancer therapy: 15 years along the road


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Liposomes as pharmaceutical drug carriers were developed to increase antitumour efficacy and decrease drug toxicity. Doxorubicin HCl liposomal injection was the first liposomal encapsulated anticancer drug to receive clinical approval. To date, virtually all traditional anticancer drugs have been encapsulated in liposomes.

 In this article Marije Slingerland, Henk-Jan Guchelaarand Hans Gelderblom focus on the liposomal anticancer drugs that are available in the clinic, including discussion on the specific adverse effects of liposomes.

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