The
View from Here
Kewal K. Jain
Nanotechnology is the creation and utilization of materials, devices,
and systems through the control of matter on the nanoscale. Given the
inherent nanoscale of the functional components of a living cell, it
was inevitable that nanotechnology was applied in biotechnology...
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more...
Upcoming Issues
Issue 4/April '07
Chemoinformatics
Issue 5/May '07
Molecular
imaging as biomarker
Issue 6/June '07
Fragment-based screening
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A
review of 2006
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Top
Reviews |
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The
role of nanobiotechnology in drug discovery
Jain, KK
Drug Discovery Today
The
application of nanotechnology in life sciences, nanobiotechnology,
is already having an impact on diagnostics and drug delivery. Now,
researchers are starting to use nanotechnology in the field of drug
discovery...
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Molecular
motors as drug delivery vehicles
Cohen, RN, Rashkin, MJ, Wen, X, Szoka, FC
Drug Discovery Today: Technologies
Molecular
motors that make up the intracellular transport system are akin
to subway cars and trains that ply the rails of cities. The inner
workings of these extraordinarily complicated systems are being
explicated at the atomic level at a phenomenal rate...
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Shaping
biodegradable polymers as nanostructures: Fabrication and applications
Lu, Y, Aguilar, CA, Chen, S
Drug Discovery Today: Technologies
The
interest in micro- and nano-devices based on biodegradable polymers
for in vivo applications is growing rapidly and the key
to these applications lies in the fashioning of features analogous
to the size of cells...
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Abstracts
of Key Research Articles
Nanomedicine:
developing smarter therapeutic and diagnostic modalities
Farokhzad OC, Langer R
Adv Drug Deliv Rev. 2006; 58(14):1456-9.
Improvement
of cancer-targeting therapy, using nanocarriers for intractable
solid tumors by inhibition of TGF-beta signaling
Kano MR, Bae Y, Iwata C, Morishita Y, Yashiro M, Oka M, Fujii
T, Komuro A, Kiyono K, Kaminishi M, Hirakawa K, Ouchi Y, Nishiyama
N, Kataoka K, Miyazono K
PNAS 2007; 104:3460-3465.
Amphiphilicity-driven
organization of nanoparticles into discrete assemblies
Zubarev ER, Xu J, Sayyad A, Gibson JD
J Am Chem Soc 2006; 128:15098-9.
Thermal
Dosimetry Predictive of Efficacy of 111In-ChL6 Nanoparticle AMF-Induced
Thermoablative Therapy for Human Breast Cancer in Mice
Denardo SJ, Denardo GL, Natarajan A, Miers LA, Foreman AR, Gruettner
C, Adamson GN, Ivkov R
J Nucl Med. 2007; 48(3):437-44.
Visualization
and dynamic size evaluation of nanoparticles in solution by single
optical fiber-illuminated video microscope analysis
Suzuto M, Nakamura A, Yamanishi Y, Suzaki E, Kataoka K, Masujima
T
Nanomedicine 2007; 2:63-70.
Nanotechnology
in clinical laboratory diagnostics
Jain, KK
Clin Chim Acta 2005; 358:37-54.
Bacterial
virus phi29 DNA-packaging motor and its potential applications
in gene therapy and nanotechnology
Guo, P
Methods Mol Biol 2005; 300:285-324.
Nanoscale
anionic macromolecules can inhibit cellular uptake of differentially
oxidized LDL
Chnari E, Nikitczuk JS, Uhrich KE, Moghe PV
Biomacromolecules 2006; 7(2):597-603.
Flexibility
and lengths of bis-peptide nanostructures by electron spin resonance
Pornsuwan S, Bird G, Schafmeister CE, Saxena
J Am Chem Soc 2006; 128:3876-7.
Role
of nanobiotechnology in developing personalized medicine for cancer
Jain, KK
Technol Cancer Res Treat 2005 Dec; 4(6):645-50.
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