Medicinal Chemistry Features for January 2012

Medicinal Chemistry Features Archive

Learning lessons from drugs that haverecently entered the market Learning lessons from drugs that haverecently entered the market

In this article, the most downloaded of Q2 2011, Simon Teague outlines that the key determinants for success in drug discovery can be defined by studying recently launched drugs.

The graphical representation of ADME-related molecule properties for medicinal chemists The graphical representation of ADME-related molecule properties for medicinal chemists

In this article, the most downloaded of Q1 2011, Timothy J. Ritchie, Peter Ertl and Richard Lewis review various approaches that have been used to represent molecule properties graphically in the context of oral ‘drug likeness’, with the goal of improving the decision making of medicinal chemists during the drug discovery process.