Charles River Laboratories, a global preclinical contract research organization, now offers BlueScreen HC Screening services for the early detection of genotoxicity. 09 September 2010
The combined effects of numerous single-letter changes in several genes could be used to predict a woman’s risk of developing the most common form of breast cancer – oestrogen-receptor-positive breast cancer. 07 September 2010
Fear can make you run or fight, or it can glue you to the spot. Now, scientists have identified the part of the brain and the type of neurons that determine how mice react to a frightening stimulus. 31 August 2010
Researchers have used a drug to reset and restart the 24 hour body clock of mice, which could eventually help with human difficulties including some psychiatric disorders, jet lag and the health impacts of shift work. 24 August 2010
Researchers have made a discovery that could lead to a brand new class of drugs to treat chronic pain caused by inflammatory conditions, such as arthritis and back pain, without numbing the whole body. 18 August 2010
During cell division, microtubules emanating from each of the spindle poles meet and overlap in the spindle’s mid zone. Now, scientists have uncovered the molecular mechanism that determines the extent of this overlap. 06 August 2010
Scientists at the European Molecular Biology Laboratory have discovered that a group of proteins named IRPs ensure that the iron balance is maintained in cells and, as such, are essential for cell survival. 04 August 2010
In May, it was announced that new research into stem cell reprogramming would reduce the need for animal testing; now, we are really beginning to see the benefits of this groundbreaking science. 28 July 2010
Cancer Research Technology and Medical Research Council Technology plan to ‘swap’ medical discoveries to accelerate the translation of early scientific research into patient benefit. 15 July 2010
SeraCare is now offering access to an extensive and constantly replenished library of remnant patient samples consisting of serum, plasma, urine, cerbrospinal fluid and amniotic fluid for pre-clinical research studies. 02 July 2010
BICOLL GmbH and EMBL have announced the successful completion of a joint research project on the identification of active compounds as inhibitors of aurora kinases. 23 June 2010
Research identifying a novel, early biomarker for insulin resistance and glucose intolerance in a non-diabetic population has now been published. 17 June 2010
Researchers at the Marlene and Stewart Greenebaum Cancer Center have studied the involvement of ‘microtentacles’, or extensions of the plasma membrane of breast cancer cells, in how cancers spread to distant locations in the body. 11 June 2010
Thermo Fisher Scientific is to provide novel protein research products to the Institute for Systems Biology, supporting a two-year project to map the human proteome that is expected to accelerate biomarker discovery and advance personalized medicine. 26 May 2010
Scientists at the Karolinska Institutet have developed a DNA vaccine that restricts the supply of blood to tumours and slows the growth of breast cancer tumours in mice. 25 May 2010
Scientists have revealed that a set of proteins act as the cell’s ‘nose’ to ‘sniff out’ molecules that trigger cell growth. 24 May 2010
New research funded by hearing loss charity RNID has revealed that even if hearing recovers after noise damage, permanent tinnitus could still develop. 11 May 2010
Gentronix’s specialized GreenScreen HC test aims to enable pharmaceutical companies to accurately test compounds for genotoxicity without disrupting simultaneous drug discovery processes. 10 May 2010
MDM2, the negative regulator of the tumour suppressor p53, is a major cancer target, and extensive evidence has shown that small molecules antagonizing this protein–protein interaction might have therapeutic value in fighting cancer. 06 May 2010
Evotec AG announced recently that it will receive funding of up to €1.5 million from the German Federal Ministry of Education and Research to advance its H3 receptor antagonist programme into the clinic. 29 April 2010
Scientists have made a major breakthrough in identifying new treatments for human African trypanosomiasis, a fatal disease that infects tens of thousands of Africans each year. 01 April 2010
Nerve-growth-factor-targeting drugs could restore confidence in the pain relief field, boosting the market and enabling the development of novel painkillers. 30 March 2010
A team of scientists has pinpointed genes likely to be responsible for colorectal cancer by identifying genomic copy number abnormalities that are common in both canine and human colorectal cancer research samples. 25 March 2010
A genetic link between schizophrenia and autism is enabling researchers to study the effectiveness of drugs used to treat both illnesses. 25 February 2010
Researchers have discovered a protein crucial in mediating the anti-inflammatory actions of nuclear lipid receptors. The findings create new possibilities for treating metabolic diseases associated with inflammation, such as diabetes. 19 February 2010
Researchers have uncovered how cells ensure inheritance of their genetic information in order to prevent diseases. 17 February 2010
Researchers have established a link between deprivation and the p53 gene that explains why women from poorer backgrounds are less likely to survive breast cancer. 16 February 2010
Scientists working at the University of Dundee have discovered a form of stem cell activity that might help lead to the early identification of cancer. 12 February 2010
A study in BMC Neuroscience has shown that chocolate-craving mice will tolerate electric shocks to get their fix. 11 February 2010
Silence Therapeutics announced recently that the United States Patent and Trademark Office has issued them a notice of allowance on a patent application covering a novel cancer target. 10 February 2010
A centre created by the Medical Research Council (MRC) and MRC Technology to fast-track the discovery and development of novel drugs opened its first call for targets recently. 08 February 2010
The most common form of malignant brain cancer in adults, glioblastoma multiforme, is not a single disease but seems to be four distinct molecular subtypes, according to a study by the Cancer Genome Atlas Research Network. 22 January 2010
AstraZeneca and the University of Virginia in Charlottesville recently announced that they have entered into a strategic research collaboration to enhance the development of new treatments primarily for coronary artery disease with a secondary focus on peripheral vascular disease. 24 December 2009
The Children’s Hospital research team believes the discovery will lead to more accurate and efficient diagnosis. 17 December 2009
The National Cancer Institute has entered into a research and development collaboration with Mayo Clinic to expand on recent research discoveries at Mayo, where researchers have demonstrated the importance of a key protein involved in pancreatic and lung cancer. 09 December 2009
An antibiotic that binds to a well-established target in a novel and unexpected way could be the inspiration for designing new, more potent antibiotic drugs. 04 December 2009
EMBL and CRG scientists reveal what a self-sufficient cell can’t do without. 03 December 2009
Researchers have discovered that patients with recent-onset schizophrenia have higher levels of inflammatory substances in their brains. 23 November 2009
One difficulty with fighting cancer cells is that they are similar in many respects to the body’s stem cells. By focusing on the differences between the two cell types, researchers have found a new way of tackling colon cancer. 17 November 2009
Researchers at the Swedish medical university Karolinska Institutet have discovered a mechanism that controls the brain's ability to create lasting memories. 10 November 2009
Could exposure to the H1N1 pandemic flu virus protect people from H5N1 bird flu? 28 October 2009
Scientists have discovered why a group of cancer drugs are so effective in treating the disease. Although they have been used for many years to treat certain tumours, researchers didn't know how they worked until now. 14 October 2009
A provocative new theory – that breast cancer cells can self-seed by wandering off around the body and returning to the primary tumour or can stay in the body for several decades after the disease seems to be cured before growing or seeding in other organs – could pave the way for new therapies to destroy the wandering cells that have escaped initial treatment. 05 October 2009
Integrated chemical genetics and proteomics approach identifies new potential drug targets in Wnt pathway. 18 September 2009
Cancer Research Technology and The Institute of Cancer Research have recently announced a major research collaboration with AstraZeneca. The three partners will combine their expertise to discover and develop potential new anti-cancer drugs to target molecular ‘chaperones’ that support the growth of cancer cells. 27 July 2009
Domainex today announced a collaboration on new exciting drug discovery programmes with the Breakthrough Breast Cancer Research Centre and The Institute of Cancer Research to identify and develop inhibitors of two recently validated breast cancer targets, tankyrase and IKK-epsilon. 27 July 2009
Researchers studying the nervous control of nematode mating behaviour have produced video footage of a male worm preparing to mate with a hermaphrodite. 22 July 2009
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