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Target Identification/ Validation

Rodent models meeting: - need for reduced drug attrition rates Rodent models meeting: - need for reduced drug attrition rates

What are the strategies for reducing drug attrition rates in the clinic through the application of transgenic rodent models?
22 February 2011

Horizon Discovery to Support 50 Centers of Excellence in Human Cellular Gene-Editing Horizon Discovery to Support 50 Centers of Excellence in Human Cellular Gene-Editing

Company will provide open access to its rAAV GENESIS human gene-editing platform as part of strategy to generate 2500 new in vitro models of cancer, neurodegenerative cardiovascular and infectious diseases.
14 December 2010

The ‘piece of the mind’ responsible for peace of mind The ‘piece of the mind’ responsible for peace of mind

Researchers have initially identified the neural pathways that control peace of mind in the human brain, which could lead to the development of new therapies in the treatment of anxiety disorders and depression.
03 November 2010

Lactate in the brain reveals aging process Lactate in the brain reveals aging process

Researchers have shown that they might be able to monitor the aging process in the brain by using MRI to measure brain lactic acid levels.
02 November 2010

Completed genome announced for Tasmanian devil Completed genome announced for Tasmanian devil

Researchers have created a draft genome sequence for the endangered Tasmanian devil and will use this to find genetic mutations in the transmissible cancer ravaging its population.
17 September 2010

Charles River now offers Gentronix BlueScreen HC Screening test Charles River now offers Gentronix BlueScreen HC Screening test

Charles River Laboratories, a global preclinical contract research organization, now offers BlueScreen HC Screening services for the early detection of genotoxicity.
09 September 2010

Genome maps could help predict risk of breast cancer Genome maps could help predict risk of breast cancer

The combined effects of numerous single-letter changes in several genes could be used to predict a woman’s risk of developing the most common form of breast cancer – oestrogen-receptor-positive breast cancer.
07 September 2010

Freeze or run? Not that simple Freeze or run? Not that simple

Fear can make you run or fight, or it can glue you to the spot. Now, scientists have identified the part of the brain and the type of neurons that determine how mice react to a frightening stimulus.
31 August 2010

Body clock drugs could ease psychiatric disorders Body clock drugs could ease psychiatric disorders

Researchers have used a drug to reset and restart the 24 hour body clock of mice, which could eventually help with human difficulties including some psychiatric disorders, jet lag and the health impacts of shift work.
24 August 2010

Scientists uncover Achilles heel of chronic inflammatory pain Scientists uncover Achilles heel of chronic inflammatory pain

Researchers have made a discovery that could lead to a brand new class of drugs to treat chronic pain caused by inflammatory conditions, such as arthritis and back pain, without numbing the whole body.
18 August 2010

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