Target Identification/ Validation News for May 2010

Target Identification/ Validation News Archive

Research expected to accelerate biomarker discoveries Research expected to accelerate biomarker discoveries

Thermo Fisher Scientific is to provide novel protein research products to the Institute for Systems Biology, supporting a two-year project to map the human proteome that is expected to accelerate biomarker discovery and advance personalized medicine.

New cancer vaccine starves tumours of blood New cancer vaccine starves tumours of blood

Scientists at the Karolinska Institutet have developed a DNA vaccine that restricts the supply of blood to tumours and slows the growth of breast cancer tumours in mice.

A blocked ‘nose’ might stop cancer cell growth A blocked ‘nose’ might stop cancer cell growth

Scientists have revealed that a set of proteins act as the cell’s ‘nose’ to ‘sniff out’ molecules that trigger cell growth.

Temporary hearing loss could cause permanent tinnitus Temporary hearing loss could cause permanent tinnitus

New research funded by hearing loss charity RNID has revealed that even if hearing recovers after noise damage, permanent tinnitus could still develop.

Gentronix develops new approach to reducing attrition rates Gentronix develops new approach to reducing attrition rates

Gentronix’s specialized GreenScreen HC test aims to enable pharmaceutical companies to accurately test compounds for genotoxicity without disrupting simultaneous drug discovery processes.

Small molecule in MDM4 Small molecule in MDM4

MDM2, the negative regulator of the tumour suppressor p53, is a major cancer target, and extensive evidence has shown that small molecules antagonizing this protein–protein interaction might have therapeutic value in fighting cancer.