The early and simultaneous consideration of potency, selectivity and ADMET (absorption, distribution, metabolism, excretion and toxicity) has become a characteristic feature of modern drug discovery. Today, prediction methods are an integral part of technology platforms for lead finding and optimization. Besides the efficient application of proven prediction methods, the field needs new developments yielding robust, precise models. Protein structure-based approaches in ADMET prediction might be one of those new paths.
19 December, 2012
Alacrita, the transatlantic firm which is changing the face of life science consulting, is delighted to launch its 2012 Life Sciences Seasonal Appeal. Alacrita is offering the unique opportunity for individuals from the life sciences industry to bid for a two-hour, one-to-one lunch with senior executives from the pharmaceutical industry.
10 December, 2012
The latest issue of Drug Discovery Today is packed full of industry focused research articles, new developments in drug discovery, and expert comment and opinion.
10 December, 2012