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Learning lessons from drugs that haverecently entered the market


Stephen Carney

In this article, the most downloaded of Q2 2011, Simon Teague outlines that the key determinants for success in drug discovery can be defined by studying recently launched drugs.

Which projects in the drug discovery field are most likely to be successful?
In this article, I provide guidelines for answering this question by
examining recent drug market entrants in detail, in particular their route
of administration, trial design, novelty, therapeutic target and toxicities. I
identify targets, trials and organizations as the key issues that are currently
leading to the poor productivity in the pharmaceutical industry. Here, I
outline some solutions and reasons for optimism, and suggest that the key
determinants for success in drug discovery can be defined by studying
recently launched drugs.

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Medicinal Chemistry

 

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