Drug discovery in the next decade: innovation needed ASAP • Review article

Drug Discovery Today, Volume 16, Issue 17-18, September 2011, Pages 779-792 | Bennani, Y.L.
22/12/2011

Follow-on drugs: How far should chemists look? • Review article

Drug Discovery Today, Volume 16, Issue 15-16, August 2011, Pages 722-732 | Giordanetto, F.; Bostrom, J.; Tyrchan, C.
22/12/2011

The impact of aromatic ring count on compound developability: further insights by examining carbo- and hetero-aromatic and -aliphatic ring types • Review article

Drug Discovery Today, Volume 16, Issue 3-4, February 2011, Pages 164-171 | Ritchie, T.J.; Macdonald, S.J.F.; Young, R.J.; Pickett, S.D.
28/05/2011

The road ahead for large pharma: long-term science and innovation • Editorial

Drug Discovery Today, Volume 14, Issue 9-10, May 2009, Pages 439-441 | Lundberg, J.M.; Reilly, C.
20/10/2009

The impact of aromatic ring count on compound developability - are too many aromatic rings a liability in drug design? • Review article

Drug Discovery Today, Volume 14, Issue 21-22, November 2009, Pages 1011-1020 | Ritchie, T.J.; Macdonald, S.J.F.
26/02/2010

Text-based knowledge discovery: search and mining of life-sciences documents • Review article

Drug Discovery Today, Volume 7, Issue 11, May 2002, Pages S89-S98 | Mack, R.; Hehenberger, M.
20/10/2009

Visualizing the drug target landscape • Review article

Drug Discovery Today, Volume 15, Issue 1-2, January 2010, Pages 3-15 | Campbell, S.J.; Gaulton, A.; Marshall, J.; Bichko, D.; Martin, S.; Brouwer, C.; Harland, L.
26/05/2010

New promising drug targets in cancer- and metastasis-initiating cells • Review article

Drug Discovery Today, Volume 15, Issue 9-10, May 2010, Pages 354-364 | Mimeault, M.; Batra, S.K.
26/08/2010

In silico repositioning of approved drugs for rare and neglected diseases • Review article

Drug Discovery Today, Volume 16, Issue 7-8, April 2011, Pages 298-310 | Ekins, S.; Williams, A.J.; Krasowski, M.D.; Freundlich, J.S.
03/08/2011

Structure-based drug design to augment hit discovery • Review article

Drug Discovery Today, Volume 16, Issue 17-18, September 2011, Pages 831-839 | Kalyaanamoorthy, S.; Chen, Y.P.P.
22/12/2011

Learning lessons from drugs that have recently entered the market • Review article

Drug Discovery Today, Volume 16, Issue 9-10, May 2011, Pages 398-411 | Teague, S.J.
03/08/2011

PubChem as a public resource for drug discovery • Review article

Drug Discovery Today, Volume 15, Issue 23-24, December 2010, Pages 1052-1057 | Li, Q.; Cheng, T.; Wang, Y.; Bryant, S.H.
11/02/2011

Evolving molecules using multi-objective optimization: applying to ADME/Tox • Review article

Drug Discovery Today, Volume 15, Issue 11-12, June 2010, Pages 451-460 | Ekins, S.; Honeycutt, J.D.; Metz, J.T.
26/08/2010

The Drug Discovery Portal: a resource to enhance drug discovery from academia • Review article

Drug Discovery Today, Volume 15, Issue 15-16, August 2010, Pages 679-683 | Clark, R.L.; Johnston, B.F.; Mackay, S.P.; Breslin, C.J.; Robertson, M.N.; Harvey, A.L.
28/10/2010

Brain drug targeting: a computational approach for overcoming blood-brain barrier • Review article

Drug Discovery Today, Volume 14, Issue 21-22, November 2009, Pages 1030-1036 | Mehdipour, A.R.; Hamidi, M.
26/02/2010

Spleen tyrosine kinases: biology, therapeutic targets and drugs • Review article

Drug Discovery Today, Volume 15, Issue 13-14, July 2010, Pages 517-530 | Riccaboni, M.; Bianchi, I.; Petrillo, P.
28/10/2010

Utility of protein structures in overcoming ADMET-related issues of drug-like compounds • Review article

Drug Discovery Today, Volume 16, Issue 11-12, June 2011, Pages 530-538 | Stoll, F.; Goller, A.H.; Hillisch, A.
03/08/2011

Lead optimization in the nondrug-like space • Review article

Drug Discovery Today, Volume 16, Issue 3-4, February 2011, Pages 158-163 | Zhao, H.
28/05/2011

How well do medicinal chemists learn from experience? • Review article

Drug Discovery Today, Volume 16, Issue 17-18, September 2011, Pages 817-821 | Cheshire, D.R.
22/12/2011

ROCK: the Roche medicinal chemistry knowledge application - design, use and impact • Review article

Drug Discovery Today, Volume 16, Issue 15-16, August 2011, Pages 691-696 | Mayweg, A.; Hofer, U.; Schnider, P.; Agnetti, F.; Galley, G.; Mattei, P.; Lucas, M.; Boehm, H.J.
22/12/2011

Outsourcing lead optimization: the eye of the storm • Review article

Drug Discovery Today, Volume 16, Issue 3-4, February 2011, Pages 147-157 | Clark, D.E.
28/05/2011

The nasty surprise of a complex drugdrug interaction • Review article

Drug Discovery Today, Volume 15, Issue 9-10, May 2010, Pages 391-395 | Bode, C.
26/08/2010

Drug discovery chemistry: a primer for the non-specialist • Review article

Drug Discovery Today, Volume 14, Issue 15-16, August 2009, Pages 731-744 | Jordan, A.M.; Roughley, S.D.
26/02/2010

The changing landscape of cancer drug discovery: a challenge to the medicinal chemist of tomorrow • Review article

Drug Discovery Today, Volume 14, Issue 21-22, November 2009, Pages 1045-1050 | Pors, K.; Goldberg, F.W.; Leamon, C.P.; Rigby, A.C.; Snyder, S.A.; Falconer, R.A.
26/02/2010

Navigating structure-activity landscapes • Review article

Drug Discovery Today, Volume 14, Issue 13-14, Pages 698-705 | Bajorath, J.; Peltason, L.; Wawer, M.; Guha, R.; Lajiness, M.S.; Van Drie, J.H.
01/12/2009