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AstraZeneca collaborates with Microsoft on ‘drag and drop’ drug discovery simulation AstraZeneca collaborates with Microsoft on ‘drag and drop’ drug discovery simulation

A new biologist-friendly, ‘drag and drop’ computer modelling system for key cancer signalling pathways is expected to speed up drug discovery and reduce the need for ‘wet’ lab experiments. Under a collaboration between AstraZeneca and Microsoft, the tool called BioModel Analyzer (BMA), has already been used to investigate how best to target signalling pathways in different acute myeloid leukaemia (AML) cell lines.

Catalent to Acquire Pharmatek, Adding Expanded Drug Development Services and Spray Drying Technology Catalent to Acquire Pharmatek, Adding Expanded Drug Development Services and Spray Drying Technology

Acquisition of West Coast Development & Clinical Manufacturing Specialist Will Add Extensive Formulation Development Capabilities and Expands Bioavailability Enhancement Solutions

Belgian scientists discover missing link in septic shock Belgian scientists discover missing link in septic shock

Researchers at VIB and Ghent University have discovered an important mechanism of sepsis, an overreaction of the body’s immune system to an infection. In this condition, the brain is unable to curb an inflammatory response, causing organ failure or ‘septic shock’. This scenario is the most frequent cause of death in intensive care units. As it turns out, information about infections is passed to our brain via extracellular vesicles, small particles in brain fluid. These insights will be published in the leading scientific journal EMBO Molecular Medicine and might give rise to new strategies to treat sepsis and even other inflammatory conditions.

The Current issue of “The view from here” is concerned with Neurology. The Current issue of “The view from here” is concerned with Neurology.

The topic of this month’s newsletter from Drug Discovery Today is “Neurology”.

Beer yeasts are dogs, wine yeasts are cats Beer yeasts are dogs, wine yeasts are cats

Yeasts were domesticated long before the discovery of microorganisms

Scientists discover how “super enzyme” speeds up DNA repair Scientists discover how “super enzyme” speeds up DNA repair

A ‘super enzyme’ known as PARP3 can help to accelerate the repair of DNA – according to scientists from the University of Sussex.

New Cognition Kit wearable enables real-time brain health measurement New Cognition Kit wearable enables real-time brain health measurement

The neuroscience company Cambridge Cognition Holdings PLC (Cambridge, UK - LSE: COG), which develops near patient technologies for the assessment of brain health, has announced results from a new technology feasibility study. The results demonstrate for the first time that consumer grade wearables such as the Apple Watch® and Microsoft Band can be used to measure accurately clinically relevant cognitive performance in everyday life using the Company’s new Cognition Kit software.

MRC Technology, AstraZeneca, Asthma UK and British Lung Foundation enter into collaboration to explore novel treatments for respiratory diseases MRC Technology, AstraZeneca, Asthma UK and British Lung Foundation enter into collaboration to explore novel treatments for respiratory diseases

Collaboration to look into link between epigenetics and respiratory disease.London, UK, 1 September 2016: A charity-industry collaboration has launched an initiative to find new epigenetic drug treatments to improve the lives of millions of people affected by respiratory diseases every year.

Nobel Laureate Roger Tsien Dies, Age 64 Nobel Laureate Roger Tsien Dies, Age 64

UC San Diego professor helped develop glowing proteins, illuminating life. Roger Tsien, PhD, co-winner of the 2008 Nobel Prize in chemistry and professor of pharmacology, chemistry and biochemistry at University of California San Diego School of Medicine for 27 years, died August 24 in Eugene, Ore. He was 64.