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Boxing move knocks cancer cells out Boxing move knocks cancer cells out

A classic boxing move, the ‘one-two punch’, could also be effective against cancer: a left jab knocks cancer cells senseless, quickly followed by a right hook that knocks them out altogether.

Life-like “on-a-chip” model of human perfused blood vessels offers new solutions for toxicity testing, drug discovery, and precision medicine Life-like “on-a-chip” model of human perfused blood vessels offers new solutions for toxicity testing, drug discovery, and precision medicine

Neuchâtel, Switzerland, 01 October 2019 – A unique, three-dimensional model of human blood vessels has been demonstrated to accurately assess a key stage in the development of inflammation and vascular disorders such as atherosclerosis. The microvessel-on-a-chip, jointly developed and optimized by Philip Morris International (PMI) and organ-on-a-chip specialists MIMETAS (Leiden, The Netherlands), can be used under flow to measure the attachment of immune cells to the blood vessel wall—an important feature of early onset atherogenesis—as well as gain unique mechanistic insights through analysis of transcriptomic profiles. In addition, the model has been shown to be effective in applications such as the toxicological assessment of consumer products.

Lab Innovations 2019 showcases sustainability in the laboratory Lab Innovations 2019 showcases sustainability in the laboratory

Source new technologies, future-proof your laboratory and find out ways to make procurement sustainable

A new initiative to revitalise drug discovery in psychiatric disease: the Psychiatry Consortium launches first call for proposals A new initiative to revitalise drug discovery in psychiatric disease: the Psychiatry Consortium launches first call for proposals

On 3rd October, the Psychiatry Consortium announced its first call for projects that focus on the identification of novel drug targets to address the unmet therapeutic needs of people with mental health conditions. Applicants can submit project proposals to the consortium from the 7th of October 2019.

2019 Nobel Prize in Physiology or Medicine jointly to William G. Kaelin, Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza 2019 Nobel Prize in Physiology or Medicine jointly to William G. Kaelin, Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza

The Nobel Assembly at Karolinska Institutet has today decided to award the 2019 Nobel Prize in Physiology or Medicine jointly to William G. Kaelin, Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza for their discoveries of how cells sense and adapt to oxygen availability.

The Current issue of “The view from here” is concerned with Ocular Drugs and Drug Delivery The Current issue of “The view from here” is concerned with Ocular Drugs and Drug Delivery

The topic of this month’s newsletter from Drug Discovery Today is “Ocular Drugs and Drug Delivery”.