The promise of stem cells for age-related macular degeneration and other retinal degenerative diseases

05 March 2013
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In this article Marco Zarbin reviews the development of hESC/iPSC-based therapies for treating age-related macular degeneration and other retinal degenerative diseases associated with abnormalities in the retinal pigment epithelium (RPE) and/or photoreceptors.

He discusses various issues such as immunogenicity, phenotype stability, tumor formation, functional integration and cytokine effect.