Targeting cancer metabolism – aiming at a tumour’s sweet-spot

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Neil Jones and Almut Schultz discuss how targeting cancer cell metabolism has emerged as a new area for anticancer drug discovery.

What has fuelled this revived interest in targeting cancer metabolism? And what are the major advances and potential challenges faced in the race to develop new therapeutics in this area? Neil Jones and Almut Schultz attempt to answer these questions by summarising recent developments in this field. They aim to illustrate why they, and others, believe that targeting metabolism in cancer presents such a promising therapeutic rationale.

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