Capillary electrophoresis and small molecule drug discovery: a perfect match?

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In this article Alfonso Espada and Manuel Molina-Martin review capillary electrophoresis fundamentals, well-established capillary electrophoresis methodologies in drug discovery of small molecules and discuss trends that, in their opinion, might emerge in the coming years.

The authors also discuss current trends of capillary electrophoresis in drug discovery beyond pure separation, such as methodological advances in sample preparation and injection, instrumental improvements in the detection step, and multidisciplinary aspects of capillary electrophoresis application in medicinal chemistry and bioanalysis.

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