Preclinical optical imaging and MRI for drug development in Alzheimer’s disease

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In this review Maarten Rotman, Thomas J.A. Snoeks and Louise van der Weerd demonstrate the preclinical use of the two imaging techniques in Alzheimer’s disease, including examples from recent applications and discuss what is needed to improve their applicability for drug discovery.

Optical and magnetic resonance imaging have the potential to be complementary non-invasive imaging modalities. Yet without advances in imaging technologies and contrast agents both have short-comings that cannot be ignored.

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