Lipid-based formulations for oral delivery of lipophilic drugs

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In the past decade there has been a growing interest in lipid-based formulations to deliver challenging compounds such as lipophilic drugs.

In this article Martin Kuentz stresses the different mechanisms of how lipid-based excipients and formulations interact with the absorption process. Case studies are presented in which enhanced bioavailability was demonstrated in vivo using this pertinent formulation approach. It is emphasized that lipid-based delivery of challenging drugs requires a development in consecutive steps.

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