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- March 2013
Drug Trials News for March 2013
The Viennese biotech boutique Themis has reported rapid progress in the development of two highly efficient vaccines against Dengue and Chikungunya fever. In the just concluded preclinical studies, the two vaccine candidates, based on a technology by the Parisian Pasteur Institute, displayed exceedingly good efficacy. With a single vaccination against Chikungunya it was possible to develop full vaccination protection. The Dengue fever vaccine candidate proved effective against all of the four known serotypes of this infection. On the basis of these excellent results, Themis will start the clinical phase I study for both vaccines before the end of this year.
27 March, 2013
Researchers from the University of Dundee and NHS Tayside are to lead a £1.2million UK-wide project, funded by the National Institute for Health Research Health Technology Assessment (NIHR HTA) Programme, to investigate the role of Sodium bicarbonate in improving physical function and quality of life for older people with advanced Chronic Kidney Disease (CKD).
20 March, 2013
Data published today in The Lancet show that over 50% of RA patients can achieve low disease activity or remission with RoActemra, compared to under 20% of those treated with the most widely prescribed anti-TNF Humira when neither drug is combined with methotrexate (51.5% vs. 19.8%, assessed by DAS28 =3.2*). The study exposed a wealth of data indicating the superiority of RoActemra over Humira, with almost four times as many patients achieving disease remission with RoActemra alone, compared to Humira alone (39.9% vs. 10.5%, assessed by DAS28 <2.6*) and almost twice as many patients achieve a 70% improvement in the signs and symptoms of their disease (32.5% vs. 17.9%, assessed by ACR70**).
19 March, 2013
Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer’s disease. Hyperammonemia is a life-threatening condition that can affect patients at any age. It is caused by abnormal, high levels of ammonia in the blood.
11 March, 2013
APEIRON Biologics AG (Apeiron) today announced that the clinical trial with their liposomal formulation of recombinant superoxide dismutase (project APN201) which started in March 2012 concluded with positive outcomes in all endpoints analyzed.
07 March, 2013