Our November issue review highlights includes:
- PET imaging with small-molecule TKIs
- Targeting mutant huntingtin: disease-modifying therapy
- Repurpose drugs for CNS diseases
- Ultra-adaptable nanovesicular systems
Cover Story
The leading story of this issue of Drug Discovery Today, Paul Slobbe, Alex J. Poot, Albert D. Windhorst and Guus A.M.S. van Dongen focus on small molecule TKIs that have been approved by the US Food and Drug Administration (FDA), their relative limited efficacy in today’s cancer treatment and the role that positron emission tomography (PET) with radiolabeled TKIs (TKI-PET) can have in a personalized treatment approach and improvement of the therapeutic successes.
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