Drug Metabolism Features for August 2009

Drug Discovery Today: highlighted review. ‘Metabolite-likeness’ as a criterion in the design and selection of pharmaceutical drug libraries

This highlighted review from Drug Discovery Today by Dobson, Patel and Kell outlines how "metabolite-likeness" in an analogous manner to "drug-likeness" and "lead-likeness" can be used to improve the value of compound libraries design by incorporating features of endogenous metabolites ("endogenites")
11 August, 2009