Drug Metabolism Features for January 2012

Drug Metabolism Features Archive

The graphical representation of ADME-related molecule properties for medicinal chemists The graphical representation of ADME-related molecule properties for medicinal chemists

In this article, the most downloaded of Q1 2011, Timothy J. Ritchie, Peter Ertl and Richard Lewis review various approaches that have been used to represent molecule properties graphically in the context of oral ‘drug likeness’, with the goal of improving the decision making of medicinal chemists during the drug discovery process.