Pharmacology/ Therapeutics News for May 2019

Pharmacology/ Therapeutics News Archive

Verseon presents oral drug candidate for diabetic eye disease that could replace eye injections Verseon presents oral drug candidate for diabetic eye disease that could replace eye injections

One in three long-term diabetes patients will develop diabetic macular edema (DME), which can lead to blindness.Present treatments are recurring injections into the eye, which can lead to infection, inflammation and are rejected by many patients.Promising efficacy and pharmacokinetic data presented at ARVO 2019 show that Verseon’s oral drug candidate could become a real alternative to current eye injections.

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

A collaborative study by research groups from the University of Cologne, VIB, Ghent University, the ?iomedical Sciences Research Center ‘Alexander Fleming’ in Athens and the University of Tokyo identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that death of macrophages, an immune cell type, can trigger the disease. Moreover, they discovered how the protein A20 prevents macrophage death and protects against arthritis. These findings open up new possibilities for the treatment of this debilitating disease.