Pharmacology/ Therapeutics News for April 2023

Pharmacology/ Therapeutics News Archive

Gene Accessibility May Explain Why Alzheimer’s Gene, APOE4, is Less Dangerous for People of African Descent Gene Accessibility May Explain Why Alzheimer’s Gene, APOE4, is Less Dangerous for People of African Descent

(MIAMI) Researchers at the John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that variations in chromatin accessibility, and thus gene expression, may explain why people of European descent with APOE4 gene variants have a greater risk of developing Alzheimer’s disease than people of African descent with similar genetics.

ECCMID 2023: Shionogi Announces Real-World Evidence Demonstrating the Efficacy of Fetcroja? (cefiderocol) Against Some of the Most Difficult-to-Treat Gram-Negative Bacterial Pathogens ECCMID 2023: Shionogi Announces Real-World Evidence Demonstrating the Efficacy of Fetcroja? (cefiderocol) Against Some of the Most Difficult-to-Treat Gram-Negative Bacterial Pathogens

A retrospective chart review interim analysis demonstrated that cefiderocol achieved clinical cure in 65% and 60% of patients with Pseudomonas aeruginosa and Acinetobacter baumannii respectively, the majority of whom were severely ill with comorbidities.

The Future of Pharma Production, Manufacturing and Packaging The Future of Pharma Production, Manufacturing and Packaging

Through a series of exclusive interviews and a survey of industry insiders, Connect in Pharma names the top pharmaceutical and manufacturing-related trends of 2023