Target Identification/ Validation News for May 2016

Loss of chromosome 8p governs tumor suppression and drug response

In a typical cancer cell, up to one-quarter of the genome is lost due to large chromosomal deletions, while the concomitant loss of hundreds of genes creates vulnerabilities that are impossible to reveal through the study of individual genes. Prof. Anna Sablina and her team at VIB/KU Leuven optimized a workflow for the generation of cell lines with targeted chromosomal deletions.
12 May, 2016

TSRI Scientists Find Root Cause of Appetite Loss During Illness

The Discovery Opens the Door to New Therapies Influencing Appetite and WeightLoss of appetite during illness is a common and potentially debilitating phenomenon—in cancer patients, especially, it can even shorten lifespan.Now scientists at The Scripps Research Institute (TSRI) have discovered how an immune system molecule hijacks a brain circuit and reduces appetite. Their research points to potential targets for treating loss of appetite and restoring a patient’s strength.
05 May, 2016

Target Identification/ Validation News for May 2016

Target Identification/ Validation News Archive

Loss of chromosome 8p governs tumor suppression and drug response Loss of chromosome 8p governs tumor suppression and drug response

TSRI Scientists Find Root Cause of Appetite Loss During Illness TSRI Scientists Find Root Cause of Appetite Loss During Illness

Loss of chromosome 8p governs tumor suppression and drug response

TSRI Scientists Find Root Cause of Appetite Loss During Illness