Novel Technologies News for February 2016

Novel Technologies News Archive

UEA scientists pave way for new generation of superbug drugs UEA scientists pave way for new generation of superbug drugs

Scientists at the University of East Anglia are getting closer to solving the problem of antibiotic resistance.

Scripps Florida Researchers Develop 'LIGHTSABR'—A Cheap, Portable Drug-Discovery System Scripps Florida Researchers Develop 'LIGHTSABR'—A Cheap, Portable Drug-Discovery System

Screening large “libraries” of compounds to find those with a desired biological activity is a powerful method for discovering new drugs, but requires a large, expensive and dedicated facility. Now, scientists at the Florida campus of The Scripps Research Institute (TSRI) have devised the central component of a screening system that would be orders of magnitude smaller and cheaper.“We’ve developed a device that can do the functional equivalent of high-throughput compound screening on an ultra-miniaturized scale,” said the study’s principal investigator Brian M. Paegel, an associate professor at TSRI.

Envigo rat models proven to be susceptible to intra-vaginal HSV-2 infection and protectable by attenuated HSV-1 against symptomatic HSV-2 Envigo rat models proven to be susceptible to intra-vaginal HSV-2 infection and protectable by attenuated HSV-1 against symptomatic HSV-2

Scientific findings establish the effectiveness of Envigo’s new approach to investigate the protective effects of vaccine candidates and anti-viral microbodies and to study asymptomatic primary genital HSV-2 infection

Crouching Protein, Hidden Enzyme Crouching Protein, Hidden Enzyme

TSRI and UC Berkeley Team Solves Structure of 'Flipping' Cellular Machine, Pointing to Possible Alzheimer’s and Cancer Therapies

Neurogenesis - Discovery of a new regulatory mechanism Neurogenesis - Discovery of a new regulatory mechanism

Bassem Hassan’s* team at VIB/KU Leuven has discovered a previously unknown mechanism that is highly conserved between species and which regulates neurogenesis through precise temporal control of the activity of a family of proteins essential for brain development: the proneural proteins. This mechanism, a simple reversible chemical modification, is critical for the production of a sufficient number of neurons, their differentiation and the development of the nervous system.