A breakthrough in the transformation of human cells, by an international team led by researchers at the University of Bristol, could open the door to a new range of treatments for a variety of medical conditions.
21 January, 2016
The topic of this month’s newsletter from Drug Discovery Today is “The best of 2015”.
20 January, 2016
Chemists at The Scripps Research Institute (TSRI) have devised a new and widely applicable technique for building potential drug molecules and other organic compounds.
20 January, 2016
‘Strain-release amination’ technique emerged from efforts to help Pfizer synthesize promising cancer drug candidate
19 January, 2016
Flavonoid-rich foods are associated with a reduced risk of erectile dysfunction – according to a new collaborative study from the University of East Anglia (UEA) and Harvard University.
13 January, 2016
On the 100th anniversary of the Endurance expedition to Antarctica led by Sir Ernest Shackleton, doctors writing in the Journal of the Royal Society of Medicine believe the inspirational explorer may have had the congenital defect commonly known as a ‘hole in the heart’. Shackleton was capable of severe exertion and made the first crossing of the mountains and glaciers of South Georgia without any health problems. During other expeditions, however, he alarmed his companions with repeated attacks of breathlessness and weakness.
13 January, 2016
Scientists at VIB and KU Leuven have identified the oxygen sensor PHD1 as a potential target for the treatment of brain infarction (ischemic stroke). Despite (minor) improvements in stroke treatment, stroke remains the fourth leading cause of death and the most common reason of severe disability. The impact of stroke is overwhelming for the patient, family and society –representing one of the largest unmet medical needs. Research led by prof. Peter Carmeliet and dr. Annelies Quaegebeur (VIB/KU Leuven) indicates that inhibition of PHD1 offers protection against stroke, via an unexpected mechanism, raising hope for future stroke treatment.
08 January, 2016