Cleveland - A team of researchers led by Goutham Narla, MD, PhD, at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, and collaborators at the Mount Sinai School of Medicine and Erasmus Medical Center, have discovered a gene variant that drives the spread of breast cancer. Published in Science Translational Medicine the study lays the early foundation for predicting which breast cancer patients may develop more aggressive disease and for designing more effective treatments.
24 January, 2013
Cancer Research UK and its commercial arm Cancer Research Technology (CRT) are launching a trial of an experimental drug shown to simultaneously block many enzymes that control cancer cell growth and death. The ‘master-switch’ experimental drug, owned by Astex Pharmaceuticals, could potentially treat a range of cancer types.
21 January, 2013
Crescendo Biologics Limited (Crescendo) announces the Crescendo Mouse, a breakthrough in antibody fragment technology which allows the efficient generation of high-quality fully human single domain antibody VH fragments from a transgenic mouse.
16 January, 2013
The latest issue of Drug Discovery Today is packed full of industry focused research articles, new developments in drug discovery, and expert comment and opinion.
10 January, 2013
A unique collaboration between the Paul Scherrer Institute, CERN’s ISOLDE facility, and the Institut Laue-Langevin, has published preclinical study results for a newly developed set of tumour-targeting radiopharmaceuticals.
10 January, 2013
While much of the recent discussion around healthcare emphasizes that the pharmaceutical industry is under pressure from the high costs of bringing a drug to market and the regulatory hurdles, we tend to forget that other industries have faced challenges too, changed and survived. There are thousands of diseases with no treatments, representing millions of patients who have no treatment. At the beginning of the 21st century our pharmaceutical business models are urgently in need of disruption to address this unmet need. We are seeing that this may come from an unlikely source, the patients and the disease foundations they support.
09 January, 2013
A pharmacological intervention directed against the proliferation of cancer cells is at the centre of a study conducted by researchers of the Drug Discovery and Development (D3) department of the Istituto Italiano di Tecnologia (IIT), based in Genoa (Italy), published on the International journal Scientific Reports, with the title “Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity”.
09 January, 2013
The Technology Strategy Board and UK Trade & Investment have announced a joint venture which sees the two organisations unite the highly successful Innovate and TechWorld events. The new, multi-sector, networking event ‘Innovate UK’ will provide opportunities for companies, including those in the healthcare sector who are looking to accelerate their growth through technology innovation, international trade and investment.
07 January, 2013
BioWales returns to the Wales Millennium Centre once again on March 19th and 20nd to show an international audience of NHS, industry and academia how Wales is delivering tomorrow’s health solutions.
04 January, 2013
Side effects are a major reason that drugs are taken off the market and a major reason why patients stop taking their medications, but scientists are now reporting the development of a new way to predict those adverse reactions ahead of time. The report on the method, which could save patients from severe side effects and save drug companies time and money, appears in ACS' Journal of Chemical Information and Modeling.
03 January, 2013