News for July 2018

News Archive

New system can identify drugs to target ‘undruggable’ enzymes critical in many diseases New system can identify drugs to target ‘undruggable’ enzymes critical in many diseases

A new drug discovery system allows scientists to specifically target members of an important family of enzymes, called phosphatases, which were previously considered mostly “undruggable”.

Following Investment, MedPharm Ltd Strengthens its Board with Three New Members Following Investment, MedPharm Ltd Strengthens its Board with Three New Members

MedPharm Ltd., a leading provider of contract topical and transdermal product design and formulation development services, is pleased to introduce three new members to its Board of Directors.

PureTech Health Collaborator Publishes in Journal Nature Regarding New Insights into Key Role of Brain Lymphatics in Alzheimer’s and Other Neurodegenerative Diseases PureTech Health Collaborator Publishes in Journal Nature Regarding New Insights into Key Role of Brain Lymphatics in Alzheimer’s and Other Neurodegenerative Diseases

Related intellectual property exclusively licensed to PureTech Health and being advanced as part of growing internal research and development division

Transcriptic Selected to Oversee Robotic Cloud Lab Platform for Lilly’s San Diego Biotechnology Center Transcriptic Selected to Oversee Robotic Cloud Lab Platform for Lilly’s San Diego Biotechnology Center

Menlo Park, CA – July 24, 2018 –Transcriptic announced today that it has entered into a multi-year collaboration agreement with Eli Lilly and Company whereby Lilly will license the Transcriptic Common Lab Environment (TCLE) to enable on-demand drug discovery operations at its San Diego Biotechnology Center. The solution Transcriptic is developing for Lilly will allow researchers across the globe to remotely design, synthesize and screen investigational molecules at the Lilly Life Science Studio (L2S2).

OBD presents latest data on the use of EpiSwitch™ in predicting patient response to immunotherapy and identifying lymphoma subtypes OBD presents latest data on the use of EpiSwitch™ in predicting patient response to immunotherapy and identifying lymphoma subtypes

EpiSwitch™ biomarkers have the potential to predict patient response to treatments with immune checkpoint inhibitors anti-PD-1 and anti-PD-L1 EpiSwitch™ biomarkers have been shown to offer prognostic stratifications in lymphoma patients Data presented at the ASH Summit on Emerging Immunotherapies for Hematologic Diseases on 13 July 2018, in Washington DC

Researchers are one step closer to developing eye drops to treat age-related macular degeneration (AMD)

Scientists at the University of Birmingham, UK, are one step closer to developing an eye drop that could revolutionise treatment for age-related macular degeneration (AMD).

The Current issue of “The view from here” is concerned with Novel Targets. The Current issue of “The view from here” is concerned with Novel Targets.

The topic of this month’s newsletter from Drug Discovery Today is “Novel Targets”.

Catalent Signs Agreement to Acquire Juniper Pharmaceuticals, Inc.$133 Million Deal Adds European Early Development Center of Excellence to Global Network Catalent Signs Agreement to Acquire Juniper Pharmaceuticals, Inc.$133 Million Deal Adds European Early Development Center of Excellence to Global Network

Catalent, Inc. (NYSE: CTLT), the leading global provider of advanced delivery technologies and development solutions for drugs, biologics and consumer health products, today announced that it has agreed to acquire Juniper Pharmaceuticals, Inc. (NASDAQ: JNPR), including its Nottingham, U.K.-based Juniper Pharma Services division. When combined with Catalent’s existing industry-leading drug development and manufacturing capabilities in the U.S. and Europe, the acquisition of Juniper will expand and strengthen Catalent’s offerings in formulation development, bioavailability solutions and clinical-scale oral dose manufacturing, and will complement its integrated global clinical and commercial supply network.

Scientists create a complete atlas of lung tumor cells Scientists create a complete atlas of lung tumor cells

Researchers from VIB, Leuven University and University Hospital Leuven studied thousands of healthy and cancerous lung cells to create the first comprehensive atlas of lung tumor cells. Their results reveal that tumors are much more complex than previously appreciated, distinguishing 52 different types of cells. This new information can be used to identify new research lines for treatment. The results of the study will be published in the leading journal Nature Medicine.

Cancer Models Platform is eliminating barriers for researchers in drug discovery Cancer Models Platform is eliminating barriers for researchers in drug discovery

Cambridge (UK) tech start-up, Repositive, has introduced new features to its Cancer Models Platform, responding to feedback from the platform’s growing user base. The platform provides oncology researchers with a holistic, searchable, comparable view of existing cancer models, whilst providing Contract Research Organisations (CROs) - the providers of the cancer models - with a tool to market, manage and analyse their models.

Advanced in vitro methodologies demonstrate new paradigms for toxicological testing Advanced in vitro methodologies demonstrate new paradigms for toxicological testing

Scientists from Philip Morris International (PMI) have presented details of a series of advanced techniques for the in vitro toxicological assessment of complex mixtures. For the scientific assessment of heated tobacco and e-cigarette aerosols, PMI has developed and tested methodologies using human cells grown in three-dimensional cultures, networks-based systems toxicological analysis, and organ-on-a-chip models combining cells from multiple human organs.