When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, HMGB1, slows down wound healing. It is, however, also essential for tumor formation at sites of previous injury. The researchers found that HMGB1 controls the actions of neutrophils, a specific type of immune cells, in skin wounds and that this is crucial for cancer initiation. Targeting this pathway could be beneficial in diabetic wound care and in patients suffering from skin blistering diseases. Their work appears in Cell Reports.
27 November, 2019
Heart failure is a global pandemic with an estimated 64.3 million cases worldwide in 2017, costing over US$100B per year. Drug developers currently lack effective humanized models for preclinical testing of targeted drug candidates in heart failure with preserved ejection fraction. The collaboration aims to provide a unique solution for future assessment of novel therapeutics.
27 November, 2019
The topic of this month’s newsletter from Drug Discovery Today is “Immunotherapies”.
22 November, 2019
Accurate and detailed protein interactions analysis under near-native conditions with an easy-to-use system
19 November, 2019
Results from the UBI Global World Benchmark Study 2019 denoting rankings of the best accelerators and incubators have been announced at the World Incubation Summit in Doha, Qatar.
19 November, 2019
Results of the survey, initiated by Merck and conducted by YouGov, indicated that there is a need to better educate people on the risk factors of type 2 diabetes, which can be prevented. The representative survey included over 9,000 people across 9 countries
14 November, 2019
Novel multiplex technology developed to help consumers make healthier choices based on their genetic profile. TTP involved with all aspects of product development, from initial concept to prototype testing and manufacture. Culmination of technology and product development partnership spanning just over 3 years
13 November, 2019
Latest DualBeam system provides significant clarity of protein interactions
13 November, 2019
Outstanding dedication to quality, science and customer service helped Reading Scientific Services Ltd (RSSL) secure Best Contract Research Organisation (CRO) at this year’s Oxford Bioscience Network (OBN) Awards.
12 November, 2019
Engine I MHP has been appointed as the preferred communications partner for Every Breath Counts, a global coalition of organisations with a mission to end preventable child pneumonia deaths by 2030.
12 November, 2019
SOMERSET, N.J. – November 4, 2019 — Catalent, the leading global provider of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, gene therapies, and consumer health products, today announced the launch of its next-generation cell line development technology, GPEx® Boost.
07 November, 2019
Golden Ticket includes one year of lab bench space at Cambridge, MA-based shared laboratory and office space
07 November, 2019
Helsinki, Finland – Nanoform, an innovative medicine enabling nanotechnology company, has won the Excellence in Pharma Award for Formulation at the prestigious CPhI Pharma Awards. Receiving this highly contested prize is an acknowledgement of Nanoform’s commitment to innovation in the industry through its best-in-class CESS® nanonization™ technology.
06 November, 2019
• Integration of PAA’s S-LAB with Sphere Fluidics’ Cyto-Mine Single Cell Analysis System increases throughput in antibody discovery and cell line development• Launch at ELRIG Drug Discovery 2019, 5–6 November, Liverpool
06 November, 2019
This innovative new feature will further support the preclinical development of precision cancer therapies
05 November, 2019
15,000 sq. ft of laboratory and office space at Coldham’s Business Park will enable continued growth and development of the Company’s integrated desktop platform for DNA synthesis
02 November, 2019
Innovative startups recognised at Alliance’s annual conference, where themes included the Lab of the Future, AI, and Real-World Data
01 November, 2019