News for November 2017

News Archive

Immune-Boosting Antibody Combination Could Improve Lymphoma Survival Immune-Boosting Antibody Combination Could Improve Lymphoma Survival

Combining two different immunotherapy treatments could dramatically improve lymphoma survival, according to a Cancer Research UK funded study published in Cancer Cell today (Thursday).

Novartis announces Phase III STRIVE data published in NEJM demonstrating significant and sustained efficacy of erenumab (AMG334) in migraine prevention Novartis announces Phase III STRIVE data published in NEJM demonstrating significant and sustained efficacy of erenumab (AMG334) in migraine prevention

Patients with episodic migraine taking erenumab reported significant and meaningful benefits over six months, with reduced migraine days and acute medication use. Fifty percent of patients taking erenumab 140mg had their migraine days cut by at least half – nearly three-fold higher odds compared to placebo. Patients on erenumab reported reduced physical impairment and improved ability to participate in daily activities based on a validated patient-reported outcome tool. Ninety percent of patients completed the six-month study; data reinforce placebo-like safety and tolerability profile of erenumab consistently seen in the entire clinical program.

£350,000 funding for tissue engineering research to predict efficacy of cancer drugs £350,000 funding for tissue engineering research to predict efficacy of cancer drugs

Breakthrough research in the field of 3D engineering of functional cancer disease models could accelerate the screening of new drugs and the approval of new treatments Technique avoids unnecessary animal testing and some clinical trials

Owlstone Medical’s Breath Biopsy Platform integrated into GSK’s Phase II Respiratory Disease Clinical Trial Owlstone Medical’s Breath Biopsy Platform integrated into GSK’s Phase II Respiratory Disease Clinical Trial

Trial will analyze breath biomarkers to improve understanding of the treatment effects of a novel GSK pipeline drug candidate for COPD

Gastric acid suppressant lansoprazole may target tuberculosis Gastric acid suppressant lansoprazole may target tuberculosis

A cheap and widely used drug, used to treat conditions such as heartburn, gastritis and ulcers, could work against the bacteria that cause tuberculosis (TB), according to new research from UCL and the London School of Hygiene & Tropical Medicine.

CRUK Manchester Institute to set up major base at Alderley Park CRUK Manchester Institute to set up major base at Alderley Park

Alderley Park’s position as a key asset in the North of England has been underlined by confirmation that it is to be the interim home for the Cancer Research UK Manchester Institute.

Call for ‘renewed focus’ on deadly threat from antibiotic resistance Call for ‘renewed focus’ on deadly threat from antibiotic resistance

The spectre of a dwindling supply of effective antibiotics is considered one of the gravest threats to public health – one that could soon claim more lives than cancer - and yet two leading experts tasked with tackling the issue fear that 2017 has seen research lag even further behind.

Verseon presents second anticoagulation candidate for clinical trials at AHA 2017 Verseon presents second anticoagulation candidate for clinical trials at AHA 2017

Verseon presented preclinical data on its second anticoagulant candidate, VE-2851, at this week’s American Heart Association conference. VE 2851 shows excellent efficacy paired with low bleeding risk in preclinical testing and is expected to enter clinical trials in 2018.

Dr Peter Simpson Appointed to SLAS Board of Directors Dr Peter Simpson Appointed to SLAS Board of Directors

Dr Peter Simpson, Medicines Discovery Catapult’s Chief Scientific Officer, has been elected to the Board of Directors at the Society for Laboratory Automation and Screening (SLAS), the world’s pre-eminent community of life sciences professionals working to advance research through the use of technology.

HTC analytical conference comes to the UK HTC analytical conference comes to the UK

The 15th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-15) will take place in Cardiff from 24th to 26th January 2018. This will be just the second time in HTC's history that the event has taken place in the UK, and it will be the premier UK analytical meeting in 2018, attracting national and internationally renowned scientists.

Improving clinical trials with machine learning Improving clinical trials with machine learning

Machine learning could improve our ability to determine whether a new drug works in the brain, potentially enabling researchers to detect drug effects that would be missed entirely by conventional statistical tests, finds a new UCL study published on 13th November in Brain.

First clinical study patient has novel drug delivery system implanted for Parkinson’s trial First clinical study patient has novel drug delivery system implanted for Parkinson’s trial

On November 8th, 2017 the first patient in a new clinical study was implanted with a novel drug delivery system, developed by Renishaw, The procedure took place at Karolinska University Hospital in Stockholm, Sweden. The implantation marks the beginning of a joint clinical study between Renishaw and Herantis Pharma. This phase I - II clinical study will investigate the treatment of Parkinson’s disease using Cerebral Dopamine Neurotrophic Factor (CDNF) delivered with Renishaw’s system.

Professor Greg Hannon to Become Director of the Cancer Research UK Cambridge Institute Professor Greg Hannon to Become Director of the Cancer Research UK Cambridge Institute

Cancer Research UK and the University of Cambridge are pleased to announce the appointment of Professor Greg Hannon as the new director of the Cancer Research UK Cambridge Institute, today (Thursday).

New charity-industry initiative to pioneer novel approach to Health Technology Assessment New charity-industry initiative to pioneer novel approach to Health Technology Assessment

‘HERCULES’ project will for the first time generate and share critical disease level data across an entire condition on behalf of all collaborating companies, simplifying all future submissionsNew approach has the potential to improve the chances of medicines in rare and orphan diseases receiving positive decisions

The Pistoia Alliance AbVance Project Reaches a Key Milestone with First Release of Antibody Structures into the Protein Data Bank The Pistoia Alliance AbVance Project Reaches a Key Milestone with First Release of Antibody Structures into the Protein Data Bank

The AbVance project aims to accelerate biologics drug discovery by increasing knowledge of antibody structures in the public domain

National Physical Laboratory and Imperial College London launch new virtual lab to establish the UK Centre for Engineering Biology, Metrology and Standards National Physical Laboratory and Imperial College London launch new virtual lab to establish the UK Centre for Engineering Biology, Metrology and Standards

NPL, the UK’s National Measurement Institute (NMI), and SynbiCITE at Imperial College London, has announced the establishment of a new £7 million virtual lab to underpin their joint Centre for Engineering Biology, Metrology and Standards to help the UK synthetic biology industry improve the manufacturing and adoption of new products – in partnership with LGC and NIBSC.

Major Networking Career Opportunity for Young Women in the South West of England Major Networking Career Opportunity for Young Women in the South West of England

A major networking opportunity for young women seeking a career in Science, Technology, Engineering and Maths (STEM) is due to be held at Dartmoor Zoo in November.

Unique collaboration opportunities available for UK SMEs working on drug discovery Unique collaboration opportunities available for UK SMEs working on drug discovery

Medicines Discovery Catapult, a new national centre established to support innovative drug discovery, is inviting UK SMEs working in medicines to collaborate on high-resolution analysis.