The topic of this month’s newsletter from Drug Discovery Today is Stem Cells.
19 August, 2015
Study revises previously published structure of Protein Kinase C enzyme, proposes new strategies to turn the enzyme “on” to treat cancer or “off” to treat neurodegenerative diseases
14 August, 2015
New brain research has mapped a key trouble spot likely to contribute to intellectual disability in Down syndrome. In a paper published in Nature Neuroscience, scientists from the University of Bristol and UCL suggest the findings could be used to inform future therapies which normalise the function of disrupted brain networks in the condition.
06 August, 2015
Prokarium Ltd, a biotechnology company developing transformational oral vaccines, today announced new funding from SynbiCITE, the UK’s Innovation and Knowledge Centre for Synthetic Biology. The £498k project is funded at £377k from SynbiCITE and £121k from Prokarium and will enable Prokarium and its collaborator Prof Robin Shattock of Imperial College to complete the pre-clinical development of an innovative Chlamydia vaccine which could enter clinical trials in 2017.
05 August, 2015
Scientists at VIB and KU Leuven have shown that reducing the expression of the PHD2 oxygen sensor impairs the ability of breast cancers to metastasize (spread) to other parts of the body. Breast cancer is the second leading cause of cancer death in women, primarily due to metastasis. These findings indicate that PHD2 inhibition may have valuable therapeutic potential. The study was published in the leading medical journal Cell Reports, which features cutting-edge biological research.
04 August, 2015