News for September 2009

News Archive

Award-winning BBSRC fellow follows in footsteps of doyen of UK structural biology Award-winning BBSRC fellow follows in footsteps of doyen of UK structural biology

The first ever BBSRC Diamond Professorial Fellow, Professor So Iwata, has been awarded the 2009 Aminoff Prize by the Royal Swedish Academy of Sciences for his work in the field of crystallography.

Karus Therapeutics and Queen Mary, University of London announce PI3 kinase collaboration Karus Therapeutics and Queen Mary, University of London announce PI3 kinase collaboration

Karus Therapeutics Ltd, a company developing small-molecule drugs to treat cancer and inflammation, announced recently that it has signed an agreement to collaborate with Professor Bart Vanhaesebroeck at Queen Mary, University of London.

New discovery reveals fate of nanoparticles in human cells New discovery reveals fate of nanoparticles in human cells

Scientists have uncovered what happens to biomimetic nanoparticles when they enter human cells.

Oxford University launches new vaccinology programme Oxford University launches new vaccinology programme

Vaccine developers with insight into the latest advances will be drivers of innovation within the vaccine industry, yet there is a lack of available training courses in the field.

IDBS and Genentech present state-of-the-art next-generation electronic lab notebooks at the 8th Annual ELN and Advanced Lab Solutions Conference IDBS and Genentech present state-of-the-art next-generation electronic lab notebooks at the 8th Annual ELN and Advanced Lab Solutions Conference

ID Business Services (IDBS) announced yesterday that IDBS customer Dr Martin Vanderlaan, Director, Analytical Operations at Genentech, will present ‘Implementing an Electronic Lab Notebook for a Large Bioprocess Organisation’ at IQPC’s ELN and Advanced Lab Solutions Conference in Brussels, Belgium.

AstraZeneca and Nektar sign worldwide agreement for Nektar drug development programmes to address opioid-induced constipation AstraZeneca and Nektar sign worldwide agreement for Nektar drug development programmes to address opioid-induced constipation

AstraZeneca and Nektar Therapeutics announced recently that they have entered into a worldwide license agreement for two drug development programmes: NKTR-118, a late-stage investigational product being evaluated for the treatment of opioid-induced constipation, and the NKTR-119 programme, an early-stage programme that is intended to deliver products for the treatment of pain without constipation side-effects.

Industry and academia team up in three-way collaboration to identify natural substances that can bind to orphan G-protein-coupled receptors Industry and academia team up in three-way collaboration to identify natural substances that can bind to orphan G-protein-coupled receptors

Findings could lead to new targets for drug discovery.

Cancer Research UK ploughs £21 million into new drug discovery programmes Cancer Research UK ploughs £21 million into new drug discovery programmes

Cancer Research UK is set to extend its drug discovery effort by investing up to £16 million in two new Drug Discovery Programmes at the Paterson Institute for Cancer Research in Manchester and the Beatson Institute for Cancer Research in Glasgow.

Cellzome technology used to unravel novel regulatory mechanism in cancer signalling pathway Cellzome technology used to unravel novel regulatory mechanism in cancer signalling pathway

Integrated chemical genetics and proteomics approach identifies new potential drug targets in Wnt pathway.

Drug Information Association (DIA) names new worldwide executive director Drug Information Association (DIA) names new worldwide executive director

The Drug Information Association (DIA) has announced the hiring of Paul Pomerantz, MBA, CAE, as its new worldwide executive director.

FDA and EMEA grant orphan drug designation for Antisense Pharma's investigational drug trabedersen in pancreatic carcinoma FDA and EMEA grant orphan drug designation for Antisense Pharma's investigational drug trabedersen in pancreatic carcinoma

Orphan drug designation ensures market exclusivity for seven to ten years after market approval.

Innovative Medicines Initiative reveals new research topics and a new Executive Director Innovative Medicines Initiative reveals new research topics and a new Executive Director

Innovative Medicines Initiative, the public–private partnership between the European Commission and the European pharmaceutical industry (represented by EFPIA), today made its first major announcement of the success of the collaboration.

Anti-Alzheimer’s agents show promising results Anti-Alzheimer’s agents show promising results

A series of iron-binding agents to prevent Alzheimer’s disease has shown promising potential for getting into brain tissue.

New data show patients with chronic low back pain maintained pain reduction on duloxetine New data show patients with chronic low back pain maintained pain reduction on duloxetine

Further pain reduction on duloxetine shown during study’s extension phase.

Hydrogels could replace animal tissues in drug tests Hydrogels could replace animal tissues in drug tests

Synthetic hydrogels could soon be used instead of animal tissue to test the sticking power of future medicines, if new materials described at the Royal Pharmaceutical Society’s annual event in Manchester, the British Pharmaceutical Conference, are developed further.

Heart disease patients don’t take their medicines Heart disease patients don’t take their medicines

At least a quarter of people with heart disease don’t take vital medicines that have been prescribed to them to prevent heart attacks and strokes.

Basil plants have anti-arthritic properties Basil plants have anti-arthritic properties

Two varieties of basil that are widely used in Ayurvedic medicine have been scientifically shown to reduce inflammation and swelling, suggesting that they could have potential in arthritis treatment.

The view from the Chairman, Sandy Munro, of the 20th Annual Drug Delivery to the Lungs conference (DDL20) in Edinburgh The view from the Chairman, Sandy Munro, of the 20th Annual Drug Delivery to the Lungs conference (DDL20) in Edinburgh

As the 20th Drug Delivery to the Lungs (DDL) conference approaches, DDL Chairman Sandy Munro offers his view on what he anticipates to be the highlights for this year’s conference; including the aims to maintain the Drug Delivery to the Lungs (DDL) technical focus while broadening its horizons. He will also be previewing what's in store for this year's special anniversary event.

University of Leicester team develops counterfeit drug detection technology University of Leicester team develops counterfeit drug detection technology

Space-age technology and crime research have combined for this new development.

Phase III head-to-head trial showed ticagrelor reduced cardiovascular death and heart attacks over clopidogrel in acute coronary syndromes patients Phase III head-to-head trial showed ticagrelor reduced cardiovascular death and heart attacks over clopidogrel in acute coronary syndromes patients

AstraZeneca recently announced results from the Phase III head-to-head trial PLATO that demonstrate that ticagrelor has achieved greater efficacy in the primary endpoint, reduction of cardiovascular events, than clopidogrel.

Shire completes submission of NDA for velaglucerase alfa for Type 1 Gaucher disease and reports positive results for remaining two Phase III trials Shire completes submission of NDA for velaglucerase alfa for Type 1 Gaucher disease and reports positive results for remaining two Phase III trials

Shire reported recently that it has completed its submission of a New Drug Application for velaglucerase alfa, its enzyme replacement therapy in development for the treatment of Type 1 Gaucher disease, with the U.S. Food and Drug Administration.

NICE issues guidance on the use of other treatment options for renal cancer NICE issues guidance on the use of other treatment options for renal cancer

The National Institute for Health and Clinical Excellence (NICE) recently issued guidance on the use of bevacizumab, sorafenib and temsirolimus for the treatment of renal cell carcinoma and the use of sorafenib and sunitinib for second-line treatment options for people with renal cell carcinoma.

NICE recommends cetuximab for the first-line treatment of metastatic colorectal cancer NICE recommends cetuximab for the first-line treatment of metastatic colorectal cancer

The National Institute for Health and Clinical Excellence (NICE) recently published final guidance on the use of cetuximab for the first-line treatment of metastatic colorectal cancer.

Ablynx announces positive Phase I results for subcutaneous administration of its anti-thrombotic Nanobody, ALX-0681 Ablynx announces positive Phase I results for subcutaneous administration of its anti-thrombotic Nanobody, ALX-0681

Ablynx recently announced positive results from its Phase I study with ALX-0681, a subcutaneous formulation of its novel anti-thrombotic Nanobody® that selectively targets von Willebrand factor.